regulations for laboratory animals ppt
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regulations for laboratory animals ppt  등록일  2021-01-25

Subpart G - Protocol for and Conduct of a Nonclinical Laboratory Study § 58.120 - Protocol. laboratory animals according to the animal welfare and ethical norms. By using safe work practices and appropriate personal protective equipment (29 CFR Part 1910 Subpart I), workers can minimize the likelihood that they will be bitten, scratched, and/or exposed to animal body fluids and tissues. Learn new and interesting things. Get ideas for your own presentations. Handling of laboratory animals and ethics 10th to 11th Novomber, 2016 Laboratory Animal Resources Section ICAR- Indian Veterinary Research Institute Izatnagar, Bareilly-243 122(U.P), India Training Program on All procedures must have prior approval from the Institutional Animal Care and Use Committee (IACUC).The blood collection method, interval between blood collection procedures, and volume of blood to remove must be listed in the approved protocol specific to each study. Plant and Animal Quarantine Regulations PART I - PRELIMINARY 1. With a physical land area of just over 700 square kilometers and a population of around 5.4 million people, this densely populated island has abundant tropical flora, parks, and gardens because of its rain… comply with the good laboratory practice (GLP) regulations prescribed in Title 21 Code of Federal Regulations, part 58 (21 CFR part 58). The Republic of Singapore, also referred to as the Garden City, is claimed as the world's only island city-state. /Length 2596 Autoclaves and Sterilizers 24 Centrifuges 24 Compressed Gases 24 Cryogens and Dry Ice 25 Electrical 25 Fire 26 Lockout/Tagout 27 Trips, Slips and Falls 28. Guide for the care and use of laboratory animals. For uncommon laboratory animal species, please contact the RAR veterinarians for more information. /Filter /FlateDecode 3 0 obj The Eighth Edition of the Guide for the Care and Use of Laboratory Animals (NRC 2011) is available for download — click here to download a PDF of the Guide. You can change your ad preferences anytime. Mr. Subhash Lal Karn Nrc guide for the care and use of laboratory animals 8th edition. Laboratory Safety Working with Small Animals All procedures on animals should be performed by properly trained personnel. Physical Hazards and Others 21. Subpart D - Equipment • A convenient size of 14×9×8 in fitting in a tray 1.5 in deep § 58.113 - Mixtures of articles with carriers. The act applies to all public and private research facilities in this country. Survey The facilities housing laboratory animals should meet or exceed current regulations and guidelines (USDA, 1990, 1991; NIH, 2002) and are required to be inspected twice a year (USDA, 1989, NIH, 2002). AALAS is a membership association of laboratory animal science professionals dedicated to the humane care and treatment of laboratory animals, as well as the quality research that leads to scientific gains that benefit people and animals GOOD LABORATORY PRACTICES Presented By:- Krushna Yadav.D.K 12MTFTFS006 2. Not-od-18-152: request for information (rfi): animal care and. This content applies to human and veterinary medicines. A publication list providing information related to Blood Collection in Laboratory Animals. can be a hazardous place to work. * *Please note that the 2011 Guide is copyrighted by the National Academy of Sciences. References 29 Appendices 30. Cage (Guinea pig) • Stock runs should be abt. It also deals with duties under the Management of Health and Safety at Work Regulations 1999 (the Management Regulations), including the need to co-operate and co-ordinate where different employers share a workplace. We generally follow CPCSEA guidelinesfor lab animal experiment and housing. • For expt. Free Piglet PowerPoint Template . § 58.49 - Laboratory operation areas. Section 5 Use of Laboratory Animals Chapter 2 Animal Handling P a g e | 2 ANIMAL HANDLING All employees who work with live animals are required to complete the Placement Health Review for Animal Handlers. We use your LinkedIn profile and activity data to personalize ads and to show you more relevant ads. The AWA contains provisions to ensure that individuals of covered species used in research … Also OECD guideline, Schedule Y, … U.C.M.S. 3. Laboratory Animals: Regulations and Recommendations for the Care and Use of Animals in Research, Second Edition, is the only publication to offer a global compilation of standards on the care, welfare and use of animals in research. Share yours for free! Introduction: Laboratory animals such as mice, rats and guinea pigs are most commonly used experimental animals for study of different biological activities in health and disease. p. 16 Guideline 3: Laboratory animal facilities must have access to reliable services, including water, electricity and sewage disposal. Animal Welfare Regulations Animal and Plant Health Inspection Service. The survey and certification of a laboratory that participates in the Clinical Laboratory Improvement Amendments (CLIA) program, is guided by legal requirements. Formed in 1964, it was revived in 1998, under the committed chairpersonship of Maneka Gandhi … With discussions of the history and ethics of animals in research, and a debate on contemporary and international issues, this book is a go-to resource for laboratory animal welfare. This covering is to be worn only when working in the ARF and exchanged for a different lab coat when working in the laboratory. The permit is valid up to five years and can comprise several projects. • The Good Laboratory Practice Regulations, Final Rule was published in the Federal Register on December 22, 1978. Looks like you’ve clipped this slide to already. The Health of Animals Act (1990) and its regulations aim primarily to protect Canadian livestock from a variety of infectious diseases that would threaten both the health of the animals and people, and Canadian trade in livestock with other countries. Download Animals PowerPoint templates and slide designs for presentations. The Public Health Service Policy on Humane Care and Use of Laboratory Animals requires institutions that receive federal funding to provide an occupational health and safety program for employees, visitors and students that work with or have exposure to research animals. The GLP regulations are found in 21 CFR Part 58.1: Good Laboratory Practice for Nonclinical Laboratory Studies. Good Laboratory Practices ppt 1. For example, the EPA has im-plemented its High Production Volume Challenge Program (HPV pro-gram), wherein it plans to test 2,800 chemicals and will perform toxicity tests on over 100,000 animals. The term GxP is a general abbreviation for 'good practice' guidelines and regulations. Users need to be aware of the legal and moral . (d) Warm-blooded animals, excluding suckling rodents, used in laboratory procedures that require manipulations and observations over an extended period of time or in studies that require the animals to be removed from and returned to their home cages for any reason (e.g., cage cleaning, treatment, etc. Laboratory safety is governed by numerous local, state and federal regulations. The administration of test substances, such as chemical ele-ments, compounds, drugs, antibodies, cells or other agents, to mice is one of the major methods for evalu-ating their biological activity. @~ (* {d+��}�G�͋љ���ς�}W�L��$�cGD2�Q���Z4 E@�@����� �A(�q`1���D ������`'�u�4�6pt�c�48.��`�R0��)� << For smaller species, the approximate volume of blood attainable for each site is listed. Access to the laboratory: Access does not have to be restricted – however, doors cannot be propped open (in violation of fire code). Standards and Certification: Laboratory Requirements (42 CFR 493) external icon Source: Government Printing Office (GPO) Federal Digital System external icon. �������� Laboratory Animals. The section of the federal regulations titled “Standards and Certification: Laboratory Requirements” is issued by the Centers for Medicare & Medicaid Services (CMS) to enact the CLIA law passed by Congress (see below). Understand the ethical issues surrounding killing or inflicting pain on animals for human benefit 2. Review and evaluate philosophical and ethical The Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS Policy) applies to activities supported by any PHS agency. 4×6 ft. and 1 ft. 8 in high • One square foot of space should be allowed for each animal • not more than 25 animals should not be kept in any one pen. If you continue browsing the site, you agree to the use of cookies on this website. 1. The users can also find useful icons for laboratory experimentation: syringes, test … Definition of GLP • GLP embodies a set of principles that provides a frame work within which laboratory … The Italian animal welfare and veterinary health rules and regulations (law n. 116/1992 and derived laws and decrees, in application of EU guideline 86/609/EEC) concerning the care and utilization of laboratory animals, require the following: 1) License for breeding, importation and exportation of laboratory animals. At the cost of their life, discoveries in science being made globally. Animal welfare laws and regulations vary tremendously across the globe. APIdays Paris 2019 - Innovation @ scale, APIs as Digital Factories' New Machi... No public clipboards found for this slide. Short Title These regulations may be cited as the Plant and Animal Quarantine Regulations. The slides include animals like dogs, monkeys, rabbits, and rats; often used in laboratory testing. • GLP is a formal regulation that was created by the FDA (United states food and drug administration) in 1978. 2 0 obj References and Additional Resources LEARNING OUTCOMES 1. Dept. This form will be reviewed by Employee Occupational Health and Wellness (EOHW), which administers all applicable medical surveillance. �@���R�t C���X��CP�%CBH@�R����f�[�(t� C��Qh�z#0 ��Z�l�`O8�����28.����p|�O×�X View Accreditation And Regulations PPTs online, safely and virus-free! {{{;�}�#�tp�8_\. Laboratory Safety Working with Small Animals All procedures on animals should be performed by properly trained personnel. The resulting guidelines are based on current knowledge about animal Laboratory Animals … dards for laboratory animal transport. Applicability (shipper and carrier responsibilities, training, combatting illegal trade) Government regulations (general and variations by country) Clipping is a handy way to collect important slides you want to go back to later. Public health service policy on humane care and use of. When handling animals hair covering, face mask, exam gloves and shoe covers are required. The care and use of laboratory animals in research is regulated under a common law frame across the EU (Directive 2010/63/EU). Find general information on blood collection methods and recommended blood collection sites for common laboratory animals. Main Office: 5205 Chairman's Court, Suite 300 Frederick, MD USA 21703 USA t: 301.696.9626 f:301.696.9627 accredit@aaalac.org ), shall receive appropriate identification. The Animal Welfare Act sets federal standards for all aspects of care for laboratory animals. Authority In pursuance of the powers conferred by section 402 of Title 22 of the Code of the Federated States of Micronesia (Supp. Laboratory workers are exposed to numerous potential hazards including chemical, biological, physical and radio-active hazards, as well as musculoskeletal stresses. Readers will benefit from a review of regulations and policy guidelines concerning lab animal use, as well as information on assessing animal welfare. Basically GLP in animal experiment varies from country to country. responsibilities of using animals in scientific procedures and realise the importance of and be competent in correct animal handling and restraint. § 58.90 - Animal care. This article describes venipuncture of the cranial vena cava (CVC) as a quick and safe technique to collect large samples of blood from ferrets. regulations, preambles, human subject protection, good clinical practice, research, investigation, trial, investigator, IRB, institutional review board Good Laboratory Practice (cGLP) prescribes guidance for conducting nonclinical laboratory studies that support applications for research or marketing permits for products regulated by the FDA, including food additives (human and animal), drugs (human and animal), medical devices for human use, biological products, and electronic products. Free Cattle PowerPoint Template. %PDF-1.7 The Swedish legislation was adjusted to the EU directive in 2013. NEW AND OLD EQUIPMENTS AND ACCESSORIES USED IN EXPERIMENTAL PHARMACOLOGY, Customer Code: Creating a Company Customers Love, Be A Great Product Leader (Amplify, Oct 2019), Trillion Dollar Coach Book (Bill Campbell). It is the research group leader/project leader who submits the application for ethical evaulation of animal experiments. /N 3 PRE-CLINICAL LAB ANIMALS ppt 1. Rules and Regulations 6. This information is used to monitor the status and trends of resident and migratory bird populations. Research Animals 19 Biological Safety Cabinets (BSCs) 21. Subpart F - Test and Control Articles § 58.105 - Test and control article characterization. See our User Agreement and Privacy Policy. Learn about the policies, regulations, and guidance that protect animals used in research, training, and testing. The LAR covers animal transport of all kinds and contains comprehensive information about the requirements for protected and endangered species as lab animals, livestock and domestic animals. Mice are the most widely used animals for a range of experiments including medical, chemical, pharmaco-logical, toxicological, biological, and genetic. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. this presentation accounts for handling, caring , feeding, common infections, different routes of injection and disposal of laboratory animals. In accordance with Federal civil rights law and U.S. Department of Agriculture (USDA) civil rights regulations and policies, the USDA, its Agencies, offices, and employees, and institutions participating in or administering USDA programs Laboratory animal facilities should be located to preclude both public access and the need for movement of animals and dirty cages through public areas. [/ICCBased 3 0 R] x���wTS��Ͻ7�P����khRH �H�. Substances Hazardous to Health Regulations 2002 (as amended) (COSHH). The Public Health Service (PHS) Policy on Humane Care and Use of Laboratory Animals requires that Assured institutions base their animal care and use programs on the Guide for the Care and Use of Laboratory Animals (Guide).The Office of Laboratory Animal Welfare (OLAW) is the National Institutes of Health (NIH) office responsible for the administration and coordination of the PHS Policy. Good Laboratory Practice : 21 CFR 58. The Institutional Animal Care and Use Committee (IACUC) is a self-regulating entity that, according to U.S. federal law, must be established by institutions that use laboratory animals for research or instructional purposes to oversee and evaluate all aspects of the institution's animal care and use program. suis primarily affects porcine species; and a third strain, B. melitensis, primarily affects goats and sheep. 2. § 58.45 - Animal supply facilities. If you continue browsing the site, you agree to the use of cookies on this website. ity tests on laboratory animals in accordance with the Toxic Substances Control Act, air and pesticide programs.' Many are downloadable. All persons entering the ARF animal room(s) will be required to wear a lab coat as a covering of street clothing. Download. Laboratory personnel have specific training in handling infected animals with pathogenic and potentially lethal agents. >> Volumes are an estimate and will also depend on the size, health, and hydration status of the animal as well as the experience and skill level of the person collecting the sample. § 58.47 - Facilities for handling test and control articles. animal Animals galvanized iron cages are recommended and sterilized. • 33 commenters. § 58.43 - Animal care facilities. Over the years, OSHA has promulgated rules and published guidance to Laboratory animal exposure risk assessment program (laerap. It was enacted into law in 1966 and has been amended by the U.S. Congress several times. It is imperative to all of us to look in the welfare of these animals. Good Clinical, Laboratory, and Manufacturing Practices (GxP) 11/30/2020; 3 minutes to read; r; In this article About GxP. The 'x' represents a particular field—clinical (GCP), manufacturing (GMP), distribution (GDP), laboratory (GLP), agriculture (GAP), and so on. *1 J�� "6DTpDQ��2(���C��"��Q��D�qp�Id�߼y�͛��~k����g�}ֺ ����LX ��X��ň��g`� l �p��B�F�|،l���� ��*�?�� ����Y"1 P������\�8=W�%�Oɘ�4M�0J�"Y�2V�s�,[|��e9�2��s��e���'�9���`���2�&c�tI�@�o�|N6 (��.�sSdl-c�(2�-�y �H�_��/X������Z.$��&\S�������M���07�#�1ؙY�r f��Yym�";�8980m-m�(�]����v�^��D���W~� ��e����mi ]�P����`/ ���u}q�|^R��,g+���\K�k)/����C_|�R����ax�8�t1C^7nfz�D����p�柇��u�$��/�ED˦L L��[���B�@�������ٹ����ЖX�! endobj Brucellosis is a contagious, infectious, and communicable disease, primarily affecting cattle, bison, and swine, and is caused by bacteria of the genus Brucella.Brucella abortus (B. abortus) primarily affects bovine species; however, goats, sheep, and horses are also susceptible.B. The CPCSEA is thus a statutory body constituted by the Government of India, with the sole purpose of controlling and supervising experiments on animals. The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. Laboratory animals have been successfully trained to perform various husbandry or clinical tasks, including moving to a new part of an enclosure (Veeder et al., 2009), presenting a body part for an injection or another procedure (Priest, 1991; From: Animal Models for the Study of Human Disease (Second Edition), 2017. The principles of Good Laboratory Practice (GLP) define a set of rules and criteria for a quality system concerned with the organisational process and the conditions under which non-clinical health and environmental safety studies are planned, performed, monitored, recorded, reported and archived. COMMON LABORATORY ANIMALS USED IN DRUG DEVELOPMENT 2. GLP: GOOD LABORATORY PRACTICE • GLP is an FDA regulation. In the United States, animal welfare oversight consists of a highly interrelated dynamic network of laws, regulations, and policies that are implemented and overseen by the Institutional Animal Care and Use Committee, veterinary staff, regulatory authorities, funding agencies, and the voluntary accreditation process. 1. Animals PPT templates and themes are compatible with Microsoft PowerPoint 2007 and 2010. Those responsible for laboratory animals should have a thorough training in their care and be familiar with the basic requirements of their animals under normal and experimental conditions. Laboratory Test Animals PowerPoint Template is an 11-slide presentation template. The Bird Banding Laboratory (BBL) is an integrated scientific program established in 1920 supporting the collection, archiving, management and dissemination of information from banded and marked birds in North America. BACKGROUND • The first major reference to animal testing occurred in the late nineteenth century when Louis Pasteur administered anthrax to sheep and showed the importance of vaccines with his germ theory. Harmonised EU rules are in place covering a range of animal species and welfare-affecting issues. Safety Hazards 24. By using safe work practices and appropriate personal protective equipment (29 CFR Part 1910 Subpart I), workers can minimize the likelihood that they will be bitten, scratched, and/or exposed to animal body fluids and tissues. In the United States, animal testing on vertebrates is primarily regulated by the Animal Welfare Act of 1966 (AWA), and the Animal Welfare Regulations which is enforced by the Animal Care division of the Animal and Plant Health Inspection Service (APHIS) of the United States Department of Agriculture (USDA). HISTORY -1970s www.fda.gov . stream See our Privacy Policy and User Agreement for details. The book provides updated information that will be of great interest to professionals across laboratory animal science and biomedical research. Ethical evaluation of animal experiments Experiments conducted under a license should be kept in an animal record. A. Slideshare uses cookies to improve functionality and performance, and to provide you with relevant advertising. Please contact the RAR veterinarians for more information and Wellness ( EOHW ) which..., electricity and sewage disposal information that will be reviewed by Employee Occupational Health and Wellness ( ). An ethical committee use your LinkedIn profile and activity data to personalize ads and provide. @ scale, APIs as Digital Factories ' New Machi... No public clipboards for! Can comprise several projects to show you more relevant ads are based on knowledge. To as the Plant and animal Quarantine regulations Part I - PRELIMINARY 1 way collect... 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